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US 3,957,729 AGranted
Process for the preparation of tridecadien derivatives
AssigneeHoffmann-La Roche Inc.
InventorsFrank Ratcliffe Atherton, Albert Pfiffner
Life of this patent
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Abstract
A process for preparing 2-cis,6-trans-10,11-epoxy-6-ethyl-3,11-dimethyl-2,6-tridecadien derivatives and mixtures of said 2-cis,6-trans-tridecadienn derivatives with its corresponding 2-trans,6-trans-geometric isomers which are useful in killing and preventing proliferation of insects, by upsetting their hormone balance including intermediates in this process.
Claims5
A process for producing an isomeric mixture containing a 2-cis, 6-trans-3,11-dimethyl-7-ethyl-trideca derivative of the formula:
- ##EQU14## A' is cyano, lower alkoxy carbonyl, amino carbonyl or lower alkyl substituted amino carbonyl
- and its corresponding 2-trans, 6-trans geometric isomer comprising reacting a compound selected from the group consisting of a 5-trans, 9-cis-2-one of the formula:
- ##EQU15## wherein B is as above its corresponding 5-trans, 9-trans geometric isomer and mixtures with a phosphine oxide of the formula:
- ##SPC2##
- wherein A' is as above, Z is lower alkyl, Y is hydrogen, halogen, lower alkoxy or lower dialkyl-amino and Y.sub.1 and Y.sub.2 are selected from the group consisting of hydrogen, halogen, lower alkoxy and nitro wherein said lower alkyl and lower alkoxy groups each have from 1 to 6 carbon atoms to form said isomeric mixture.
2 more elements
Dependencies are inferred from the claim text.