Method and device for rapid chromatographic separation
AssigneeEntreprise de Recherches et D'Activities Petrolieres Elf
InventorPatrick Valentin
Life of this patent
Estimating the term…
Abstract
A method of rapid chromatographic separation by exchange of substances between two fluid phases circulating in coutercurrent flow, at least one phase being liquid, consists in injecting the substances to be separated into one of the phases, in causing the two phases to circulate on each side of a porous body having a thickness within the range of 1 to 200 microns while limiting the thickness of at least one liquid phase to a constant value within the range of 0.1 to 100 microns and in collecting after circulation the substances which have been separated in each of the two phases.
Claims11
A method of rapid chromatographic separation by exchange of substances between two fluid phases circulating in countercurrent flow, at least one phase being liquid, the separation of the substances between said two phases being distinguised by high selectivity together with high productivity, wherein said method comprises injecting the substances to be separated into one of the phases, causing the two phases to circulate on each side of a porous body having a thickness within the range of 1 to 200 microns while limiting the thickness of at least one liquid phase to a constant value within the range of 0.1 to 100 microns, and collecting after circulation the substances which have been separated in each of the two phases.
A device for producing rapid chromatographic separation by exchange of substances between two fluid phases circulating in countercurrent flow comprising a porous body in the form of a cylinder having a wall which limits an internal and an external chamber to the wall of said cylinder, one of said phases being in said internal chamber, means to move said one phase in said internal chamber in a first direction parallel to said wall, the other of said phases being in said external chamber, means to move said other phase in said external chamber in a second direction parallel to said wall and opposite said first direction, the thickness of said porous body being within the range of 1 to 200 microns, and the thickness of each of said phases being within the range of 0.1 to 100 microns.
A device for producing rapid chromatographic separation by exchange of substances between two fluid phases circulating in countercurrent flow comprising a vessel having an interior, a first phase inlet manifold and a first phase outlet manifold communicating with said interior of said vessel, a second phase inlet manifold and a second phase outlet manifold communicating with said interior of said vessel, and a plurality of parallel flat porous bodies disposed within said interior of said vessel, said porous bodies being constructed and arranged to provide the sole means in said vessel to separate said first phase inlet and outlet manifolds from said second phase inlet and outlet manifolds, said porous bodies being further constructed and arranged to maintain open communication between said first phase inlet and outlet manifolds and between said second phase inlet and outlet manifolds, whereby said porous bodies define a plurality fo stacked parallel consecutively numbered chambers in which said first phase is within the even numbered chambers and said second phase is within the odd numbered chambers, means to circulate said first phase through said even numbered chambers from said first phase inlet manifold to said first phase outlet manifold in a first direction parallel to said porous bodies, means to circulate said second phase through said odd numbered chambers from said second phase inlet manifold to said second phase outlet manifold in a second direction parallel to said porous bodies and opposite said first direction, the thickness of each of said phases being a constant value within the range of 0.1 to 100 microns, and said porous bodies each having a thickness within the range of 1 to 200 microns.
Dependencies are inferred from the claim text.