Cysteamine derivatives for oral treatment of seborrhea
AssigneeL'oreal
InventorsGregoire Kalopissis, Georges Manoussos
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Abstract
A method for treating a scalp characterized by an excessive secretion of sebum, to improve the condition thereof by reducing said excessive secretion comprising orally administering to a human being having a scalp so characterized a therapeutic composition comprising an ingestible carrier admixed with, as a non-toxic active compound, cysteine or cysteamine derivatives, the active compound is present in amounts of about 0.75-3 weight percent of the composition which is administered at a rate of about 1-5 mg/kg/day based on the weight of the human being during a period of about 15 days.
Claims2
A method for treating a scalp, characterized by an excessive secretion of sebum, to improve the condition thereof by reducing said excessive secretion of sebum comprising orally administering to a human being having a scalp so characterized a therapeutic composition comprising an ingestible carrier admixed with a non-toxic active compound selected from the group consisting of
- 2-methylthio ethylamine cinnamate,
- 2-hexadecylthio ethylamine hydrochloride,
- 2-allylthio ethylamine malate,
- 9-octadecene-2-ylthio ethylamine hydrochloride,
- 2-dodecylthio ethylamine hydrochloride,
- 2-isopentylthio ethylamine mandelate,
- 2-octadecylthio ethylamine salicylate,
- 2-.beta.-hydroxyethylthio ethylamine hydrochloride,
- 2-(2,3-dihydroxy propylthio) ethylamine p-toluenesulfonate,
- 2-(2-hydroxy propylthio) ethylamine oxalate,
- 2-(2,2-dimethoxy ethylthio) ethylamine hydrochloride,
- 2-(2,2-dimethoxy ethylthio) ethylamine undecylenate,
- 2-(2,2-diethoxy ethylthio) ethylamine undecylenate,
- 2-(2,2-diethoxy ethylthio) ethylamine acetate,
- 2-undecenylthio ethylamine,
- 2-.beta.-acetamidoethylthio ethylamine tropate,
- 2,2'-thio diethylamine fumarate,
- 3-.beta.-aminoethylthio propylamine hydrochloride,
- 3-allylthio propylamine,
- 3-(2,2'-dimethoxy ethylthio) propylamine,
- 3-(2,2'-dimethoxy ethyl thio) propylamine sulfate,
- 2-t-butylthio ethylamine hydrochloride,
- 2,2'-thio diethylamine dihydrochloride,
- 2-methylthio ethylamine,
- 2-cetylthio ethylamine hydrochloride,
- 2-methylthio ethylamine phenylacetate and
- 2-methylthio ethylamine undecylenate,
- said active compound being present in an amount ranging from 0.75 to 3 percent by weight of said composition and said composition being administered at a rate of 1-5 mg/kg/day based on the weight of the human being.
Dependencies are inferred from the claim text.