New anti-malarial agents
AssigneeAktiebolaget Astra
InventorIbrahim Mohamed Nabih
Life of this patent
Estimating the term…
Abstract
Compounds of the formula ##SPC1## Wherein A designates that the fused six-membered ring could be either unreduced, partially reduced or totally reduced and wherein R.sup.1 is --N(CH.sub.3).sub.2, --N(C.sub.2 H.sub.5).sub.2, ##EQU1## or --N(CH.sub.2 CH.sub.2 Cl).sub.2 and R.sup.2 is ##SPC2## And R is an acyl group with 1-5 carbon atoms, and pharmaceutically acceptable salts thereof; processes for their preparation; pharmaceutical preparations containing at least one of these compounds and the use thereof in the treatment of and protection against malaria infection.
Claims3
A compound selected from the group consisting of a compound of the formula ##SPC9##
- wherein A designates that the fused six-membered ring could be either unreduced, partially reduced, or totally reduced, and wherein R.sup.1 is --N(CH.sub.3).sub.2, --N(C.sub.2 H.sub.5).sub.2, ##EQU3## or --N(CH.sub.2 CH.sub.2 Cl).sub.2 and R.sup.2 is ##SPC10##
- and pharmaceutically acceptable salts thereof.
The compound ##SPC11##
- or pharmaceutically acceptable salts thereof.
The compound ##SPC12##
- or pharmaceutically acceptable salts thereof.
Dependencies are inferred from the claim text.