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US 3,947,566 AGranted
Effervescent medicaments
AssigneePhoenix Research Corporation
InventorsEdward J. Sarna, Norman H. Ishler, Joseph Jellema
Life of this patent
Estimating the term…
Abstract
Medicament compositions exhibiting effervescence comprise a medicament and a liquefied gas distributed therethrough. The liquefied gas is present in the compositions at pressure and temperature conditions at which it would normally exist only in the gaseous state. As the liquefied gas separate from the compositions, effervescence occurs.
Claims8
An effervescing medicament composition confined under pressure in an aerosol dispensing container,
- said medicament composition consisting essentially of (a) a liquefied gas having a boiling point of from about -50.degree.F. to about 80.degree.F. and an aqueous or alcoholic phase (b) containing a medicament selected from the group consisting of a cough preparation, an analgesic and a stomach alkalizer and being substantially free of an agent capable of emulsifying the liquefied gas (a) in said phase (b), said phase (b) being substantially non-soluble with (a) and being dispersible with (a) with agitation thereof, liquefied gas (a) having a density greater than (b) and the quantity of (a) being at least about 5 percent by weight in excess of the quantity required to propel (b) from said container,
- said medicament composition being characterized by effervescence when said aerosol container is agitated whereupon (a) is dispersed in (b), and, while (a) and (b) are interdispersed, discharging contents of the container as a liquid stream into a vessel, some of the dispersed liquefied gas (a) remaining dispersed and entrained as a liquid in said liquid stream after the contents leave the container.
Dependencies are inferred from the claim text.