Zinc complexes of basic aluminum chlorides and methods of making same
AssigneeArmour Pharmaceutical Company
InventorsJohn L. Jones, Andrew M. Rubino, Charles B. Lindahl
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AssigneeArmour Pharmaceutical Company
InventorsJohn L. Jones, Andrew M. Rubino, Charles B. Lindahl
Estimating the term…
Alcohol soluble complexes of basic aluminum chlorides may be prepared by adding zinc bromide or chloride, or zirconyl bromide or hydroxybromide, or zinc or zirconyl mixtures of the above to an aqueous solution of five-sixths basic aluminum chloride, and drying the resulting mixture to a substantially friable solid. The complexes preferably have an Al/Zn or Al/Zr mol ratio of about 3:1 to 20:1, and the complex solids preferably contain about 12 to 30 weight percent water by Karl Fischer analysis. Such complex solids have a high degree of solubility in anhydrous alcohol and a high compatibility with halogenated hydrocarbons, thus making the complexes suitable for aerosol formulations and particularly antiperspirant compositions.
A method of preparing alcohol soluble solid complexes of five-sixths basic aluminum chlorides comprising the steps of providing an aqueous solution of five-sixths basic aluminum chloride having the general empirical formula:
Dependencies are inferred from the claim text.