Alkylated 3,20-diketo-.DELTA..sup.4 -steroids of the pregnane series

Abstract

The invention relates to novel alkylated steroids of the pregnane series having the formula: ##SPC1## , wherein X = a member of the group consisting of H and halogen; Y = a member of the group consisting of H.sub.2, H(OH), H(OAcyl) and O; R.sub.1 = a member of the group consisting of H, CH.sub.3 and halogen; R.sub.2 = alkyl having 1-4 carbon atoms; R.sub.3 = a member of the group consisting of H (except when Y = H.sub.2), OAcyl, Oalkyl, and CH.sub.3 ; R.sub.4 = a member of the group consisting of H and alkyl having 1-4 carbon atoms and in which at least one of the substituents R.sub.3 and R.sub.4 is alkyl; and C.sub.1 -c.sub.2 and C.sub.6 -C.sub.7 are selected from a saturated and an unsaturated bond. The novel compounds possess strong anti-inflammatory properties and are useful in the treatment of inflammatory conditions especially those associated with the skin and allergic reactions.

Dependencies are inferred from the claim text.