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US 3,947,469 AGranted
3-(1,3-Dithian-2-yl)-4-cyclo-pentene-2-carboxylic acids, esters and amides
AssigneeRecherche et Industrie Therapeutiques (R.I.T.)
InventorsLeon Ghosez, Eric Cossement, Robert Biname
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Abstract
The invention relates to the stereoisomers of novel cyclopentene derivatives and to the preparation thereof. The cyclopentene derivatives are obtained by cycloaddition reaction between cyclopentadiene and a mono-or bis-thioalkyl (or aryl) ketene and reaction between the obtained product and a nucleophile agent. The compounds of the invention are intermediate products valuable for the preparation of different compounds, among which compounds of the prostaglandin type.
Claims8
A compound of the formula ##SPC5##
- where Nu is hydroxy, lower alkoxy of 1 to 4 carbon
- atoms, amino, lower alkylamino of 1 to 4 carbon atoms, or dilower alkylamino, each alkyl having 1 to 4 carbon atoms;
- m is 2 or 3;
- and
- the wavy line indicates an .alpha. or .beta.-configuration.
2 more elements
Dependencies are inferred from the claim text.