3-Alkylsilyl-2-oxazolidonone compounds and synthesis thereof
OwnerAntonio Luis Palomo Collinventor
Life of this patent
Estimating the term…
Abstract
Silylating agents, such as 3-alkylsilyl-2-oxazolidinones, are useful for the preparation of penicillins and cephalosporins at low temperatures and in a short time. The process for preparing these compounds comprises reacting 2-oxazolidinone or 5-methyl-2-oxazolidinone with trimethylchlorosilane, dimethylchlorosilane or triethylchlorosilane, in the presence of an organic tertiary base acting as a hydrogen chloride removal agent.
Claims5
A 3-alkylsilyl-2-oxazolidinone of the formula ##EQU6## where R.sub.1 and R.sub.2 are each selected from the group consisting of hydrogen, phenyl, and alkyl having one to three carbon atoms, R.sub.3 and R.sub.4 are each alkyl having one to three carbon atoms and R.sub.5 is an element selected from the group consisting of alkyl having one to three carbon atoms and chlorine.
3-trimethylsilyl-2-oxazolidinone.
3-triethylsilyl-2-oxazolidinone.
3-trimethylsilyl-5-methyl-2-oxazolidinone.
5-phenyl-3-triethylsilyl-2-oxazolidinone.
Dependencies are inferred from the claim text.