US 3,944,563 A · 1-Amino-pyrazolic derivatives

Abstract

1-AMINO-5-ALKOXY-PYRAZOLE COMPOUNDS OF THE FORMULA: ##EQU1## wherein R.sub.1 represents a lower alkyl group having 1 to 4 carbon atoms, R.sub.2 and R.sub.3, which may be identical or different, represent a hydrogen atom, a lower alkyl group, a phenyl group, a phenyl group substituted by one or more groups selected from lower alkyl, halogen, nitro and lower alkoxy; R.sub.4 represents an amino group, a mono-lower alkyl amino group or a di-lower alkyl amino group; as well as their salts with a mineral or organic acid. A method for the preparation thereof, consisting essentially in internally transforming, in the presence of hydrazine, a 5-hydrazino-isoxazole (or 5-halogenoisoxazole) derivative and alkylating the 5-hydroxy-derivative obtained with a suitable diazoalkane.

Claims3

Dependent claims

1-amino-5 alkoxy-pyrazole compounds of the formula:

##EQU5## wherein R.sub.1 represents a lower alkyl group having 1 to 4 carbon atoms, R.sub.2 and R.sub.3, which may be identical or different, represent a hydrogen atom, a lower alkyl group, a phenyl group, a phenyl group substituted by one or more groups selected from lower alkyl, halogen, nitro and lower alkoxy;
R.sub.4 represents an amino group, a mono-lower alkyl amino group or a di-lower alkyl amino group;
as well as their pharmaceutically acceptable salts with a mineral or organic acid.

Dependencies are inferred from the claim text.

1-Amino-pyrazolic derivatives

Life of this patent

1-Amino-pyrazolic derivatives

Life of this patent

Abstract

Claims3