N-(quinolyn)-anthranilates
AssigneeRoussel Uclaf
InventorsAnne Farthouat, Jean Meier
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Abstract
N-(7- or 8-substituted-quinolyl-4)-anthranilates of the formula ##SPC1## Wherein X in the 7 or 8 position is trihalomethyl or trihalomethylthio, Z is --(CH.sub.2).sub.n -- or --(CH.sub.2).sub.m --O--(CH.sub.2).sub.p --, n is a whole number from 2 to 6, m and p are whole numbers from 2 to 3 and Y.sub.1 and Y.sub.2 are alkyl having 1 to 6 carbon atoms, as well as their non-toxic, pharmaceutically acceptable acid addition salts having analgesic and anti-inflammatory activity and their preparation.
Claims7
Substituted anthranilates selected from the group consisting of N-(7- or 8-substituted-quinolyl-4)-anthranilates of the formula ##SPC5##
- wherein X is trifluoromethyl in the 7 or 8 position, Z is a member selected from the group consisting of --(CH.sub.2).sub.n --, where n is an integer from 2 to 6, and --(CH.sub.2).sub.m --O--(CH.sub.2).sub.p --, where m and p are each an integer from 2 to 3, and Y.sub.1 and Y.sub.2 are alkyl having from 1 to 6 carbon atoms, and their non-toxic, pharmaceutically acceptable acid addition salts.
Dependencies are inferred from the claim text.