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US 3,944,544 AGranted
Bis-cephalosporins
AssigneeE. R. Squibb & Sons, Inc.
InventorsDonald J. Perrella, Joseph E. Dolfini
Life of this patent
Estimating the term…
Abstract
Derivatives of difunctional compounds such as dicarboxylic acids, diisocyanates or diisothiocyanates wherein each functional group is reacted with 7-aminocephalosporanic acid or 7-aminodesacetoxycephalosporanic acid possess antibacterial activity.
Claims7
A compound of the formula:
- ##EQU2## wherein R is furyl or thienyl;
- X is ##EQU3## Q is --CH.sub.3 or --CH.sub.2 OCOCH.sub.3 ;
- Z is hydrogen, an alkali metal salt, an alkaline earth metal salt, NH.sub.4, alkyl of 1 to 4 carbons, trichloroethyl, pivaloyloxymethyl, benzyl, p-nitrophenyl, trimethylsilyl, trimethylstannyl, methoxymethyl, triethylamine, procaine, dibenzylamine, N-benzyl-.beta.-phenethylamine, N,N-dibenzylethylenediamine, or N-ethylpiperidine;
- and n is 2, 3 or 4.
1 more element
Dependencies are inferred from the claim text.