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US 3,944,064 AGranted
Self-monitored device for releasing agent at functional rate
AssigneeAlza Corporation
InventorsJohn D. Bashaw, Alejandro Zaffaroni, Alan S. Michaels
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AssigneeAlza Corporation
InventorsJohn D. Bashaw, Alejandro Zaffaroni, Alan S. Michaels
Estimating the term…
A delivery device for the controlled and continuous release of a useful agent at a functional rate is comprised of an erodible capsule housing a self monitored delivery device attached to a collapsed support. The device is comprised of a hollow container having a wall formed of a self-monitored release rate controlling material permeable to the passage of the agent by diffusion, or the wall is formed of a microporous material whose micropores are a means for holding a self-monitored release rate controlling medium permeable to the passage of the agent by diffusion. The device on its release from the bioerodible capsule in the environment of use releases an effective amount of agent at a functional rate over a prolonged and continuous period of time.
A device for the controlled and continuous release of a useful agent to an environment of use wherein the device is comprised of a container having a wall enclosing a hollow area, a reservoir formed by the container wall's inner surface as a means for storing the agent, the container wall additionally formed in at least a part of a self-monitored release rate controlling essentially imperforate homogenous material permeable to the passage of the agent by diffusion for releasing agent from the reservoir, a support member for carrying the container with the wall of the container covering at least a portion of the surface of the support and suitably fixed thereto, said support member movable from a collapsed position to an expanded position and movable from an expanded position to a collapsed position after a period of agent release time, and wherein agent is metered from the reservoir through the wall in a useful amount for a prolonged period of time when the device is in the selected environment of use.
A useful device for the release of a useful agent, wherein the device is comprised of a container having a wall enclosing a hollow area, a reservoir formed by the container wall's inner surface as a means for storing the agent, said container wall defining the reservoir formed in at least a part of a microporous material whose micropores contain an agent release rate controlling medium permeable to the passage of the agent at a predetermined rate by diffusion, a support member for carrying the container with a wall of the container covering at least a portion of the support and suitably united thereto, with the support member movable from a collapsed position to an expanded position and returnable to a collapsed position after a period of agent release time, and wherein agent is metered from the reservoir by passage through a medium housed in the micropores of the wall of the container in an effective amount for a prolonged period of time when the device is placed in the environment of use.
A delivery device for the controlled and continuous release of a beneficial agent, the device comprising in combination,
Dependencies are inferred from the claim text.