Derivatives of 2-amino-(1,2,3,4-tetrahydronaphthalene), the preparation and use thereof
AssigneeA. Christiaens Societe Anonyme
InventorsPierre M. Vanhoof, Pierre M. Clarebout
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Abstract
This invention relates to new derivatives of 2-amino-(1,2,3,4-tetrahydronaphthalene), namely 2-[N-phenyl-N-(R.sub.1,R.sub.2 -aminoalkyl or alkanoyl)]-amino-(1,2,3,4-tetrahydronaphthalenes), in which R.sub.1 and R.sub.2 represent a lower alkyl group or form together with the attached nitrogen atom a nitrogenous heterocyclic ring, with the proviso that R.sub.1 may also represent hydrogen, as well as to the acid addition salts of these new derivatives. These new derivatives are active for the treatment of heart arrhythmy.
Claims2
Derivatives of 2-amino-(1,2,3,4-tetrahydronaphthalene) of the formula:
- ##SPC8##
- in which n=2 or 3, R.sub.1 and R.sub.2 each represent a lower alkyl group containing 1 to 4 carbon atoms with the proviso that R.sub.1 may also represent hydrogen, and R.sub.3 represents hydrogen or a lower alkoxy group and the pharmaceutically acceptable acid addition salts of said compounds of formula (1).
2-[N-phenyl-N-(.gamma.- ethylaminopropyl)]-amino-(1,2,3,4-tetrahydronaphthalene), and the pharmaceutically acceptable the acid addition salts of this compound.
Dependencies are inferred from the claim text.