Indole fused heterocyclic diuretic compounds
AssigneeAmerican Home Products Corporation
InventorsDavid R. Herbst, Herchel Smith
Life of this patent
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Abstract
Substituted 1,2,4,5,6,7,8,9-octahydro-3H-azecino[5,4-b]-indoles and substituted 1,2,3,4,5,6,7,8-octahydroazonino[5,4-b]-indoles are prepared by cleavage of the corresponding quaternary alkyl iodide salts with lithium in liquid ammonia. The products possess diuretic activity.
Claims6
1,2,4,5,6,7,8,9-octahydro-3,9-dimethyl-3H-azecino[5,4-b]indole.
1,2,3,4,5,6,7,8,-octahydro-3,8-dimethylazonino[5,4-b]indole.
1,2,3,4,5,6,7,8-octahydro-3,7,8-trimethylazonino[5,4-b]indole.
1,2,3,4,5,6,7,8-octahydro-11-methoxy-3,7,8-trimethylazonino[5, 4-b]indole.
1,2,4,5,6,7,8,9-octahydro-3-methyl-3H-azecino[5,4-b]indole.
1,2,3,4,5,6,7,8-octahydro-3-methylazonino]5,4-b]indole.
Dependencies are inferred from the claim text.