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US 3,943,131 AGranted
Trifluoromethylmercaptoacetamidocephalosporins
AssigneeSmithKline Corporation
InventorsRobert M. De Marinis, John R. E. Hoover
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Abstract
This invention is directed to antibacterial compounds, in particular, to 7-trifluoromethylmercaptoacetamidocephalosporins.
Claims7
A pharmaceutical composition comprising an antibacterially effective amount of the compound of the formula ##SPC2##
- in which:
- A is S-Het;
- Het is a 5 or 6 membered heterocyclic ring containing 1-4 hetero atoms selected from the group consisting of N, O and S and being unsubstituted or substituted with one or two groups selected from the group consisting of alkyl, alkoxy, alkylthio, each alkyl residue being one to four carbon atoms;
- C.sub.3 -C.sub.4 cycloalkyl, halogen, hydroxy, mercapto, trifluoromethyl and NR.sub.2 ;
- and
- R is hydrogen or C.sub.1 14 C.sub. 6 alkyl, or a pharmaceutically acceptable salt thereof and sterile water or sterile saline as carrier therefor.
3 more elements
Dependencies are inferred from the claim text.