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US 3,943,130 AGranted
[[(Thioalkoxy)thiocarbonyl]oxy]acetyl cephalosporin derivatives
AssigneeE. R. Squibb & Sons, Inc.
InventorsUwe D. Treuner, Hermann Breuer
Life of this patent
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Abstract
[[(Thioalkoxy)thiocarbonyl]oxy]acetyl cephalosporin derivatives of the general formula ##SPC1## Wherein R is hydrogen, lower alkyl, phenyl-lower alkyl, tri-(lower alkyl)stannyl, tri(lower alkyl)silyl, a salt forming ion or the group ##EQU1## is hydrogen, lower alkyl, phenyl, thienyl, furyl or pyridyl; R.sub.2 is lower alkyl or phenyl-lower alkyl; R.sub.3 is hydrogen, lower alkanoyloxy, azido or pyridyl; R.sub.4 is lower alkyl, phenyl or phenyl-lower alkyl; are useful as antibacterial agents.
Claims10
A compound of the formula ##SPC4##
- wherein R is hydrogen, lower alkyl, phenyl-lower alkyl, tri(lower alkyl) stannyl, tri(lower alkyl)silyl, ##EQU9## alkali metal, alkaline earth metal or (lower alkyl)amine;
- R.sub.1 is hydrogen, lower alkyl, phenyl, R.sub.5 -thienyl, R.sub.5 -furyl or R.sub.5 -pyridyl;
- R.sub.2 is lower alkyl or phenyl-lower alkyl;
- R.sub.3 is hydrogen or lower alkanoyloxy;
- R.sub.4 is lower alkyl, phenyl or phenyl-lower alkyl;
- and R.sub.5 is hydrogen or lower alkyl.
3 more elements
Dependencies are inferred from the claim text.