Dispensing packages containing novel cyclic progestogen-interrupted estrogen oral contraceptive regimens
AssigneeSyntex Corporation
InventorEugene J. Segre
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AssigneeSyntex Corporation
InventorEugene J. Segre
Estimating the term…
This invention relates to a method of fertility control by use of novel cyclic progestogen-interrupted estrogen oral contraceptive regimens. Considering the first day of menstrual flow as day one of a 28 day medication administration cycle, a combined formulation of estrogen and progestogen substances is administered on the 3rd, 4th, 5th or 6th day of the cycle and every second or third day thereafter through, and including, the 23rd, 24th, 25th, 26th, 27th or 28th day of the cycle, and a formulation having only a progestogen substance as the active component is administered on the 4th, 5th, 6th, or 7th day of the cycle and every day thereafter on which a combination formulation is not administered, through, and including, the 22nd, 23rd, 24th, 25th, 26th, 27th or 28th day of the cycle. In a particular regimen, a combination of estrogen and progestogen is administered starting with the 5th day of the cycle and continuing every other day through the 25th day of the cycle, and starting with the 6th day of the cycle and continuing every other day through the 24th day of the cycle only progestogen is administered. The remaining seven days are dosage-free or the regimen is completed by use of placebos or other nonhormonal supplements. Dispensing packages for holding unit dosage forms for oral ingestion of one unit dosage form daily in the appropriate sequence during a single cycle of medication administration are also described.
In combination, a dispensing package having cyclic progestogen-interrupted estrogen oral contraceptives in unit dosage forms therein, said unit dosage forms being adapted for oral administration of one unit dosage form daily in a predetermined sequence during a 28 day medication administration cycle, said sequence being predetermined by the manner in which said unit dosage forms are stored in said dispensing package, said dispensing package bearing directions to take one unit dosage form daily in the directed sequence;
In combination, a dispensing package having cyclic progestogen-interrupted estrogen oral contraceptives in unit dosage forms therein, said unit dosage forms being adapted for oral administration of one unit dosage form daily in a predetermined sequence during a 28 day medication administration cycle, said sequence being predetermined by the manner in which said unit dosage forms are stored in said dispensing package, said dispensing package bearing directions to take one unit dosage from daily in the directed sequence;
Dependencies are inferred from the claim text.