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US 3,941,889 AGranted
5-(Substituted phenoxy)-4-amino pyrimidines as anti-ulcer agents
AssigneePfizer Inc.
InventorChristopher Andrew Lipinski
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Abstract
The preparation of novel 5-(substituted phenoxy)-4-amino and substituted amino pyrimidines is described. These compounds, possessing anti-secretory and anti-ulcer activity, are effective anti-ulcer agents.
Claims1
A method for the control of ulcers in an animal which comprises administering orally or intraperitoneally to an animal in need of such control a composition containing a diluent amount of a pharmaceutically-acceptable carrier and an amount effective to control said ulcers of a compound selected from the group consisting of ##SPC4##
- and a pharmaceutically-acceptable acid addition salt thereof, wherein X and Y are each hydrogen, chlorine, bromine, fluorine, alkyl containing from 1 to 6 carbon atoms, trifluoromethyl or alkoxy containing from 1 to 3 carbon atoms in the alkyl moiety;
- R.sub.1 and R.sub.2 are each hydrogen to alkyl containing from 1 to 6 carbon atoms.
Dependencies are inferred from the claim text.