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US 3,941,883 AGranted
Aromatic dicarboxamides as anticonvulsants
AssigneeCiba-Geigy Corporation
InventorsHeinz Werner Gschwend, Malvin J. Hillman
Life of this patent
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Abstract
N-(4-aminophenyl)-aromatic dicarboxamides, e.g., those of the formula ##SPC1## Or salts thereof are anticonvulsants.
Claims4
An anticonvulsant pharmaceutical composition in the form of a tablet or capsule comprising a spasmolytically effective amount of a compound corresponding to the formula ##SPC7##
- wherein Ar is 1,2-phenylene substituted by at least one member selected from lower alkyl, alkoxy, alkylmercapto, -sulfinyl or -sulfonyl, halogeno, trifluoromethyl, carbamoyl, sulfamoyl, mono- or dialkylcarbamoyl or -sulfamoyl;
- unsubstituted or alkylated and/or halogenated 2,3- or 3,4-(furylene, thienylene or pyridylene), R is lower alkyl, (hydroxy, alkoxy, alkylmercapto, -sulfinyl or -sulfonyl)-alkyl, halogeno or trifluoromethyl, n is 0 and C.sub.n H.sub.2n separates Ar from CO by one or no carbon atom, or acid addition salts thereof, together with a pharmaceutical excipient.
Dependencies are inferred from the claim text.