Method for use of 11-lower alkyl steroids
AssigneeG. D. Searle & Co.
InventorGeorge E. Short
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Abstract
The method of controlling estrus and ovulation in female bovines by the administration of 11-lower alkyl steroids and 11-lower alkyl steroid compositions for use therein. Drug delivery system for the controlled elution of 11-lower alkyl steroids comprising the steroid adsorbed in a copolymer of a monoester of an olefinic acid and a diester of an oelfinic acid. The method of controlling estrus and ovulation in female bovines by the implantation of said drug delivery system in the bovines, followed by removal at a predetermined period, alternatively augmenting the estrus response by administration of an estrogenic compound.
Claims5
A method of controlling ovulation and estrus in female bovines which comprises the subcutaneous administration of an 11-lower alkyl steroidal progestational compound selected from the group comprising 17.alpha.-acetoxy-11.beta.-methyl-19-norpregn-4-ene-3,20-dione and 3-(3-oxo-11.beta.-methyl-17.beta. hydroxyestr-4-en-17.alpha.-yl) propionic acid .gamma. lactone, being essentially devoid of estrogenic activity, to said female bovines.
Dependencies are inferred from the claim text.