Back to results
US 3,941,823 AGranted
Method for producing isonitrosomalonic esters
AssigneeTakeda Chemical Industries, Ltd.
InventorsNaoto Hashimoto, Masaaki Kuritani, Noriaki Toukai
Life of this patent
Estimating the term…
Abstract
Isonitrosomalonic acid esters, which are useful as a starting material for synthesizing sweet peptides and other chemicals, are prepared by allowing a nitrosating agent to act on a corresponding alkyl alkoxycarbonyl acetoimidate.
Claims11
A method for the production of a compound of the formula of ##EQU8## wherein X is O or S, R and R.sup.1 are different from each other and represent a straight chain, branched or cyclic alkyl having up to 20 carbon atoms, which are unsubstituted or substituted by chlorine or bromine, which comprises reacting a compound of the formula:
- ##EQU9## wherein B is -COOR.sup.1 or ##EQU10## and X, R and R.sup.1 have the same meaning as defined above, which a nitrosating agent in an amount at least equal to the sum of one molecular equivalent for the methylene group and one molecular equivalent per imidate or thioimidate group of the compound of the formula (I), said reaction being conducted with cooling or at room temperature, in a solvent.
Dependencies are inferred from the claim text.