Imidazo [5,1-f]-as-triazines
AssigneeAllen & Hanburys Limited
InventorsRobert William Clarke, David Hartley, Alexander William Oxford
Life of this patent
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AssigneeAllen & Hanburys Limited
InventorsRobert William Clarke, David Hartley, Alexander William Oxford
Estimating the term…
Compounds of the general formula: ##SPC1## In which: R.sub.1 and R.sub.2 which may be the same or different, represent a hydrogen atom or an alkyl group which may optionally be substituted by an aryl group, or represents an alkanoyl, aroyl or alkanesulphonyl group; R.sub.3 represents a hydrogen atom, or an alkyl group which may optionally be substituted by an aryl group, or represents an alkenyl, aryl or alkylthio group; R.sub.4 represents a hydrogen atom or an alkyl group; and R.sub.5 represents a hydrogen atom or an aryl or alkyl group, which alkyl group may optionally be substituted by a cycloalkyl group; And physiologically acceptable salts and derivatives thereof and addition products formed by nucleophilic addition. These compounds act as spasmolytics and phosphodiasterase inhibitors and have cardiotonic and diuretic properties. They are also of use in the treatment of skin disorders and gout.
A compound of the formula:
The process for the preparation of compounds of the formula:
Dependencies are inferred from the claim text.