Roller culture bottle insert
AssigneeThe Curators of the University of Missouri
InventorWilliam D. Noteboom
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Abstract
A plastic spiral insert for use in existing roller culture bottles effective to increase the total surface area available for cell culture. The insert consists of a continuous coil of plastic sheet material that may be thermally set so as to retain its spiral configuration within the roller bottle and may also include integral raised portions on the sheet material effective to maintain uniform spacing between successive layers of the coil. The invention also includes retraction apparatus for removing the insert from small necked bottles.
Claims5
Apparatus for use in a roller culture bottle that is partially filled with a culture medium for the growing of cells or microorganisms and comprising:
- a continuous elongated sheet of plastic material wound into a tight cylindrical coil and thermally set so as to retain a spiral configuration for insertion into the culture bottle and further adapted to expand into an enlarged spiral configuration after insertion into the bottle, and
- spacing means formed integrally with said sheet for separating successive layers of said spiral when present within the culture bottle so as to permit the passage of culture medium therethrough as the bottle is rolled about an axis coincident with the axis of said spiral.
Dependencies are inferred from the claim text.