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US 3,940,395 AGranted
4-Amino-2-phenyl-6-thiopryimidines
AssigneeAmerican Home Products Corporation
InventorsArthur A. Santilli, Dong H. Kim
Life of this patent
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Abstract
The invention is directed to 4-amino-2-phenyl-6-thiopyrimidine compounds having the formula ##SPC1## Where R.sup.1 -R.sup.3 are as defined in the specification. The compounds have pharmacodynamic activity as central nervous system depressants. That is, they produce a calming effect in the host.
Claims20
A compound selected from the group consisting of those having the formula:
- ##SPC4##
- wherein R.sup.1 is selected from the group consisting of hydrogen, dichloro, halogen, methyl, ethyl, propyl and methoxy;
- R.sup.2 is selected from the group consisting of amino, 4-methylpiperazino, 4-ethylpiperazino, methoxyethylamino, methoxypropylamino, 4-hydroxyethylpiperazino, hydroxyethylamino, hydroxypropylamino, hexahydroazepinyl, dimethoxyethylamino;
- diethyoxyethylamino, methylamino, ethylamino, propylamino and butylamino;
- and R.sup.3 is selected from the group consisting of phenyl, halophenyl, ethylphenyl, methoxyphenyl, ethoxyphenyl, propoxyphenyl, benzyl, halobenzyl, methylbenzyl, methoxybenzyl, ethoxybenzyl and propoxybenzyl.
2 more elements
Dependencies are inferred from the claim text.