Cyclic carbonyl compounds
AssigneeBurroughs Wellcome Co.
InventorsHarold Francis Hodson, John Frederick Batchelor
Life of this patent
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Abstract
Certain fluorenone and anthraquinone compounds, each of which is 2-substituted by a carboxyl group or a salt, ester or optionally substituted amide thereof and each of which is optionally substituted in the 5,6-,7- or 8- position, by a second carboxyl group, salt, ester or optionally substituted amide thereof, the substitutent in the 5,6-7- or 8- position of the fluorenone compounds, also being selected from cyano, halogen, nitro, alkyl, alkoxy and acyl, are useful for the relief or prophylaxis of allergic conditions.
Claims11
A method of preventing the symptoms of asthma or allergic rhinitis in a mammal having asthma or allergic rhinitis which comprises administering to said mammal a prophylactically effective amount of a compound of formula ##SPC14##
- where Z.sup.1 is selected from the group consisting of carboxyl, a pharmaceutically acceptable carboxylate salt and alkyl carboxylate wherein the alkyl moiety has 1 to 6 carbon atoms;
- and Z.sup.2 is selected from the group consisting of hydrogen and a substituent Z.sup.1 as defined herein.
A method of preventing the symptoms of asthma or allergic rhinitis in a mammal having asthma or allergic rhinitis which comprises administering to said mammal a prophylactically effective amount of a compound of the formula ##SPC15##
- wherein Z.sup.1 and Z.sup.2 are the same or different and each is selected from the group consisting of carboxyl, pharmaceutically acceptable carboxylate salt, and alkyl carboxylate having 1 to 6 carbon atoms in the `alkyl` moiety.
Dependencies are inferred from the claim text.