2,4-Diamino substituted pyridol(3,2-d)pyrimidine as antithrombotic agents
AssigneeBoehringer Ingelheim GmbH
InventorsJosef Nickl, Erich Muller, Berthold Narr, Josef Roch
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AssigneeBoehringer Ingelheim GmbH
InventorsJosef Nickl, Erich Muller, Berthold Narr, Josef Roch
Estimating the term…
Pharmaceutical compositions containing as an active ingredient a compound of the formula ##SPC1## Wherein R.sub.1 and R.sub.2, which may be identical to or different from each other, are each morpholino, thiomorpholino, 1-oxido-thiomorpholino, 1,1-dioxidothiomorpholino or piperidino, where each of these may optionally have a lower alkyl substituent attached thereto; piperazino; N'-acyl-piperazino; N'-carbamoyl-piperazino; N'-lower alkyl-piperazino; dialkanol-amino; or alkylenediamino; and R.sub.3 is hydrogen or methyl; Or a non-toxic, pharmacologically acceptable acid addition salt thereof; and methods of using the same to inhibit thrombocyte aggregation and adhesiveness.
An antithrombotic pharmaceutical dosage unit composition consisting essentially of an inert pharmaceutical carrier and an effective antithrombotic amount of a compound of the formula ##SPC32##
Dependencies are inferred from the claim text.