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US 3,939,267 AGranted
4-Ethers of 3-amino-5-sulfamoylbenzoic acids
AssigneeCiba-Geigy Corporation
InventorLincoln Harvey Werner
Life of this patent
Estimating the term…
Abstract
4-Phenylethers of 3-amino-5-sulfamoylbenzoic acids, e.g. those of the formula ##SPC1## R = an aliphatic or araliphatic radical X = o or S Ph.degree. = a phenylene radical R' = h, alkyl or Ph.degree.--R" One of R.degree. and R" is NH.sub.2 and the other is H alkyl esters or salts thereof are diuretic agents.
Claims4
A pharmaceutical composition comprising a diuretically effective amount of a compound corresponding to the formula ##SPC15##
- in which R.sub.1 is lower alkyl, lower alkenyl, cycloalkyl or cycloalkyl-lower alkyl, each of which with 3 to 7 ring carbon atoms, Ph is unsubstituted phenylene or phenylene substituted by one member of lower alkyl, each of R.sub.2, R.sub.3 and R.sub.4 is hydrogen or lower alkyl, and X is oxygen or sulfur, or the lower alkyl esters or therapeutical useful ammonium, alkali or alkaline earth metal or acid addition salts thereof, together with a pharmaceutical excipient.
Dependencies are inferred from the claim text.