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US 3,939,266 AGranted
Substituted sulfonylacetamido cephalosporins
AssigneeSmithKline Corporation
InventorsRobert M. De Marinis, John R. E. Hoover
Life of this patent
Estimating the term…
Abstract
Cephalosporin compounds having various substituted sulfonylacetamido groups at position 7 have been prepared and have antibacterial activity.
Claims5
A pharmaceutical composition comprising an antibacterially effective amount of a compound of the formula ##SPC2##
- where:
- X is lower alkyl of C.sub.1 -C.sub.6 ;
- A is CH.sub.2 S-Het;
- Het is a 5- or 6-membered heterocyclic ring containing one to four atoms selected from the group consisting of N, O and S, unsubstituted or substituted with from one to two groups selected from the group consisting of lower alkyl, cycloalkyl or alkenyl, each having one to four carbon atoms;
- lower alkoxy or alkoxyalkyl, each alkyl or alkoxy having one to four carbon atoms;
- hydroxy;
- CF.sub.3 ;
- NHR;
- NR.sub.2 ;
- SR;
- or halogen;
- R is hydrogen or alkyl (C.sub.1 -C.sub.4);
- and
- M is hydrogen, alkali metal cation or nontoxic ammonium cation
- and a pharmaceutically acceptable carrier therefor.
12 more elements
Dependencies are inferred from the claim text.