Process for the manufacture of human transferrin labelled with indium 113m
AssigneeHoechst Aktiengesellschaft
InventorElfriede Niemann
Life of this patent
Estimating the term…
Abstract
A process for the manufacture of human transferrin labelled with indium 113 m is provided, wherein an acid eluate of an indium 113 m generator having an activity concentration of 0.1 to 50 m Curie per ml is added dropwise to an aqueous solution containing 3 to 10 mg of sodium bicarbonate per 5 to 100 mg of human transferrin per ml. The solution may also contain hydrochloric acid or sodium chloride and a bacteriostatic agent.
Claims2
A method for making human transferrin labelled with indium 113 m, which comprises adding an eluate of an indium 113 m generator dropwise to an aqueous human transferrin solution in a volume ratio of 1:1, said eluate having an activity concentration of 0.9 to 50 milli Curie per ml and containing 0.2 to 0.01 N hydrochloric acid and said aqueous transferrin solution containing 3 to 10 mg of sodium bicarbonate per 5 to 100 mg of human transferrin per ml.
Dependencies are inferred from the claim text.