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US 3,939,193 AGranted
D-Homosteroids
AssigneeHoffmann-La Roche Inc.
InventorsLeo Alig, Andor Furst, Marcel Muller
Life of this patent
Estimating the term…
Abstract
A novel class of D-homosteroids is disclosed. These compounds have potent endocrinal activity, particularly as anti-inflammatory agents.
Claims12
A D-homosteroid of the formula ##SPC16##
- wherein R.sup.6 is hydrogen, fluorine, chlorine, bromine or methyl;
- R.sup.11 is hydroxy;
- R.sup.9 is hydrogen, fluorine, chlorine or bromine when R.sup.11 is hydroxy and R.sup.9 is chlorine or bromine when R.sup.11 is fluorine or chlorine;
- R.sup.21 is halogen or R when R.sup.11 is hydroxy and R.sup.21 is halogen, hydroxy or hydrocarbon C.sub.1.sub.-15 acyloxy or R when R.sup.11 is fluorine or chlorine;
- R is a sulfate or phosphate radical or the radical of a dicarboxylic acid or tricarboxylic acid in the form of a water-soluble salt;
- R.sup.17a is hydroxy or hydrocarbon C.sub.1.sub.-15 acyloxy;
- and the broken line in the 1,2-position denotes an optional bond.
4 more elements
Dependencies are inferred from the claim text.