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US 3,939,164 AGranted
7 AND 8-Halo substituted 1,2,3,4-tetrahydroisoquinoline compounds
AssigneeSmithKline Corporation
InventorsCarl Kaiser, Robert G. Pendleton
Life of this patent
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Abstract
1,2,3,4-Tetrahydroisoquinoline compounds having 7 and 8 halo substituents are inhibitors of phenylethanolamine N-methyltransferase.
Claims4
A compound of the formula:
- ##SPC3##
- in which:
- R.sub.1 and R.sub.2 are chloro, bromo or iodo, R.sub.1 and R.sub.2 being the same or different, or R.sub.1 and R.sub.2 are both fluoro and
- R.sub.3 is hydrogen, methyl or ethyl or a pharmaceutically acceptable, acid addition salt thereof.
1 more element
Dependencies are inferred from the claim text.