4',5'-Dihydrospiro[androst/estr-4-ene-17,2'(3'H)-furan]3,4'-dione and congeners, and intermediates thereto
AssigneeG. D. Searle & Co.
InventorEdward A. Brown
Life of this patent
Estimating the term…
Abstract
4',5'-Dihydrospiro[androst/estr-4-ene-17,2'(3'H)-furan]-3,4'-dione and congeners; the antiviral, antiandro genic, diuretic, and/or antiestrogenic activity inherent therein; and means of preparing them via novel intermediates are disclosed.
Claims10
A compound of the formula ##SPC3##
- wherein the dotted lines in ring A indicate that the compound is .DELTA..sup.1, .DELTA..sup.4, or .DELTA..sup.1,4.
4',5'-Dihydrospiro[5.alpha.-androstane-17,2'(3'H)-furan]-3,4'-dione.
4',5'-Dihydrospiro[5.alpha.-androstane-17,2'(3'H)-furan]-3.beta.,4'- diol.
4',5'-Dihydrospiro[estr-4-ene-17,2'(3'H)-furan]-3,4'-dione.
A compound of the formula ##SPC4##
4',5'-Dihydro-3-methoxyspiro[estra-2,5(10)-diene-17,2'(3'H)-furan]-4'-ol .
4',5'-Dihydro-3-methoxyspiro[estra-1,3,5(10)-triene-17,2'(3'H)-furan]-4' -ol.
3-Methoxyspiro[estra-1,3,5(10)-triene-17,2'(5'H)-furan].
Dependencies are inferred from the claim text.