Penicillin derivatives
AssigneeYamanouchi Pharmaceutical Co., Ltd.
InventorsMasuo Murakami, Ichiro Isaka, Khozi Nakano, Isao Souzu, Akio Koda, Teruaki Ozasa, Teruya Kashiwagi, Yukiyasu Murakami
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AssigneeYamanouchi Pharmaceutical Co., Ltd.
InventorsMasuo Murakami, Ichiro Isaka, Khozi Nakano, Isao Souzu, Akio Koda, Teruaki Ozasa, Teruya Kashiwagi, Yukiyasu Murakami
Estimating the term…
The penicillin derivatives represented by the formula ##SPC1## Wherein ring A represents a 5- or 6-membered single or fused ring which may contain one or more nitrogen atoms, an oxygen atom, or a sulfur atom; R.sup.1, R.sup.2, and R.sup.3, which may be the same or different, each represents a hydrogen atom, a hydroxy group, a lower alkyl group, a nitro group, a halogen atom, or an oxo group; and B represents a p-hydroxyphenyl group or a 1,4-cyclohexadien -1-yl group, and their nontoxic pharmaceutically acceptable salts. The compounds are antibiotics having excellent antibacterial activity in particular with respect to the Pseudomonas genus.
.alpha.-(4-Oxo-4H-thiopyran-3-carboxamido)-p-hydroxybenzylpenicillin and its pharmaceutically acceptable acid addition salts.
Dependencies are inferred from the claim text.