Compositions and process for liquid scintillation counting
AssigneeNew England Nuclear Corporation
InventorJoel M. Kauffman
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Abstract
Liquid scintillation counting compositions which include certain polyethoxylated poly(oxypropylene) emulsifiers allow stable dispersion of aqueous or other samples merely by shaking. Preferred are mixtures of such emulsifiers, which give homogeneous, monophasic-appearing dispersions over wide ranges of temperature and aqueous sample content. Certain of these emulsifiers, without being mixed, are of particular advantage when used in analysis of samples obtained through radioimmunoassay techniques, which are extremely difficult to disperse. Certain of these emulsifiers, also without being mixed, uniformly give homogeneous, monophasic appearing aqueous counting samples over much wider ranges of aqueous sample content and temperature than prior sample emulsifiers.
Claims14
A liquid scintillation counting composition, comprising at least one solvent, a scintillating solute and a surface active agent, said surface active agent comprising a mixture of a first material having the following structural formula:
- ##EQU3## wherein y is from about 15 to 56, and x and z are from about 1 to 35, and a second, different material having the following structural formula:
- ##EQU4## wherein y' is from about 15 to 56, and x' and z' are from about 1 to 35.
A liquid scintillation counting composition, comprising at least one solvent, a scintillating solute and a surface active agent, said surface active agent comprising a material having the following structural formula:
- ##EQU5## wherein y is selected from the ranges of 18 to 28 and 32 to 40, and the total [CH.sub.2 --CH.sub.2 --O] content is from about 10 to 30% by weight of the molecule.
A method of liquid scintillation counting comprising mixing a sample to be analyzed with a liquid scintillation composition comprising a mixture of a first material having the following structural formula:
- ##EQU6## in which y is from about 15 to 56 and x and z are from about 1 to about 35, and a second material having the following structural formula:
- ##EQU7## in which y' is from about 15 to about 56 and x and z are from about 1 to 35, and exposing the liquid scintillation composition to a scintillation counter.
A method of liquid scintillation counting comprising adding a sample to be analyzed to a liquid scintillation composition comprising a material having a material having the following structural formula:
- ##EQU8## in which y is selected from the ranges of about 18 to about 28 and about 32 to about 40, and the total [CH.sub.2 --CH.sub.2 --O] content is about 10 to 30% by weight of the total molecule.
Dependencies are inferred from the claim text.