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US 3,937,842 AGranted
Method of treating conditions of delayed hypersensitivity using bis-basic substituted acenaphthene derivatives
AssigneeRichardson-Merrell Inc.
InventorIrving Shemano
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Abstract
Novel 3,6-bis basic ketone derivatives of acenaphthene useful in treating conditions of delayed hypersensitivity are disclosed.
Claims4
A method of treating conditions of delayed hypersensitivity which comprises administering to a patient in need thereof a 3,6-bis-basic ketone of acenaphthene having the formula:
- ##SPC9##
- wherein A is a straight or branched alkylene chain having from 1 to 6 carbon atoms;
- and Y is selected from the group consisting of:
- ##EQU10## wherein R.sub.1 and R.sub.2 are individually selected from the group consisting of hydrogen, lower alkyl having from 1 to 6 carbon atoms, cycloalkyl having from 3 to 6 carbon atoms, alkenyl having from 3 to 6 carbon atoms in which the unsaturation is in a position other than the 1-position of the alkenyl group;
- and the pharmaceutically acceptable salts thereof, in an amount effective to suppress delayed hypersensitivity.
2 more elements
Dependencies are inferred from the claim text.