Substituted chromone-3-carbonitriles, carboxamides and carboxylic acids useful for preventing asthmatic symptoms

Abstract

Substituted chromone-3-carbonitriles, carboxamides and carboxylic acids having the structural formula: ##SPC1## Wherein R.sub.1 represents hydrogen, halogen, lower alkyl, hydroxy, lower alkoxy, or acyloxy; R.sub.2 represents hydrogen, lower alkyl, fluorinated lower alkyl, alkoxycarbonyl, carboxy, or lower alkyl carboxylic acid; Z represents cyano, carboxy, alkoxycarbonyl, or ##EQU1## wherein X represents amino, N-lower-alkylamino, hydroxylamino, N-lower-alkylhydroxylamino, ureido, piperidino, or anilino, with the proviso that when R.sub.2 represents hydrogen, Z represents cyano or ##EQU2## wherein X has the same meaning as given above; and wherein R.sub.2 and Z together may form a substituted pyrrole ring; and the corresponding non-toxic, pharmaceutically acceptable salts.

Dependencies are inferred from the claim text.