Substituted pyrano[3,2-c] [1,2]benzothiazine 6,6-dioxides
AssigneeWarner-Lambert Company
InventorsDaniel Kaminsky, Sylvester Klutchko, Maximilian VON Strandtmann
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Abstract
Novel pyrano[3,2-c][1,2]benzothiazine 6,6-dioxides are disclosed, substituted on the 3 position by a lower alkyl, carboxaldehyde, or hydroxymethyl group and, optionally substituted on the 5 position by a lower alkyl group. The corresponding aldehyde thiosemicarbazone derivatives of these compounds are also disclosed. Pharmaceutical compositions containing the substituted pyrano[3,2-c][1,2]benzothiazine 6,6-dioxides of this invention are useful in the treatment of hyperacidity; certain of these compounds also demonstrate anti-allergy activity.
Claims2
A method for preventing asthmatic symptoms which comprises administering to a mammal in need thereof an effective amount of a compound of the formula:
- ##SPC22##
- wherein R represents lower alkyl;
- and R' represents carboxaldehyde and
Dependencies are inferred from the claim text.