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US 3,937,818 AGranted
Benzylamine narcotic antagonists
AssigneeAmerican Home Products Corporation
InventorsHorace Fletcher, Jerry L. Malis, John P. Yardley
Life of this patent
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Abstract
A process for antagonizing the pharmacologic effects of a narcotic agent in warm-blooded animals, and compositions for effecting this process are disclosed.
Claims8
A process for antagonizing the effect of a narcotic agent in warm-blooded animals which comprises administering to a warm-blooded animal in need thereof a sufficient amount of a compound of the formula:
- ##SPC4##
- wherein R is ethyl or benzyl;
- and the pharmacologically acceptable acid addition salts thereof.
A narcotic antagonist composition for administration to a warm-blooded animal comprising:
- a. an amount, sufficient to elicit a narcotic antagonist response in a warm-blooded animal affected by a narcotic, of the compound of the formula:
- ##SPC5## and the pharmacologically acceptable acid addition salts thereof;
- and b. a pharmaceutically acceptable carrier.
Dependencies are inferred from the claim text.