Addition compound of a nucleotide and an amino acid and the use thereof in protection against actinic radiation
AssigneeKolmar Laboratories, Inc.
InventorOtto K. Jacobi
Life of this patent
Estimating the term…
Abstract
An addition compound of one mol of a nucleotide and 1 to 4 mols of an amino carboxylic acid or an amino sulfo acid. The compound is used as an agent for protection against actinic radiation.
Claims7
A topical composition for protection against actinic radiation, comprising a dermatologically acceptable inert carrier suitable for application to human skin, and having dispersed therein from 0.1% to 99.9% by weight of a compound of the formula:
- [Nucleoside (PO.sub.3).sub.n.Me.sub.n.sub.+ 1 ]AS.sub.m
- wherein the nucleoside is a glycoside of a compound selected from the group consisting of adenine, guanine, cytosine, uracil and thymine;
- Me is a cation selected from the group consisting of hydrogen, an alkali metal, and ammonium;
- n is an integer from 1 to 3;
- m is an integer from 1 to (n + 1);
- and AS is acid having from 1 to 20 carbon atoms and selected from the group consisting of an amino carboxylic acid and an amino sulfo acid.
A method of protecting human skin against actinic radiation, comprising the step of applying to the skin a dermatologically acceptable inert carrier containing an effective amount of a compound having the formula:
- [Nucleoside (PO.sub.3).sub.n.Me.sub.n.sub.+ 1 ]AS.sub.m
- wherein the nucleoside is a glycoside of a compound selected from the group consisting of adenine, guanine, cytosine, uracil and thymine;
- Me is a cation selected from the group consisting of hydrogen, an alkali metal, and ammonium;
- n is an integer from 1 to 3;
- m is an integer from 1 to (n + 1);
- and AS is an acid having from 1 to 20 carbon atoms and selected from the group consisting of an amino carboxyoic acid and an amino sulfo acid.
Dependencies are inferred from the claim text.