Method of making dentifrice compositions containing insolubilized salts of 1,6-di-(p-chlorophenyl biguanido) hexane
AssigneeColgate-Palmolive Company
InventorMichael Harrison
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Abstract
Preparation of a dentifrice composition containing an insolubilized salt of 1,6-di-(p-chlorophenyl biguanido) hexane antimicrobial agent such as the disarcosinate monomeric salt or monofluorophosphate polymeric salt. The insolubilized salt may be pre-formed or formed in situ in the dentifrice composition. The insolubilized material is antimicrobially effective and provides desirable cosmetic effect.
Claims15
A method of preparing a dentifrice composition which comprises mixing in a dentifrice vehicle a non-toxic insolubilized salt of 1,6-di-(p-chlorophenyl biguanido) hexane antimicrobial agent in amount corresponding to about 0.01-5% by weight of the free base thereof wherein said antimicrobial agent is in the form of a monomer salt selected from the group consisting of disarcosinate salt and dibenzoate salt and a polymer salt.
Dependencies are inferred from the claim text.