Salts of iodomethanesulfonic acid with organic bases
AssigneeSchering Corporation
InventorsHermann Ulbrich, Wolfgang Beich
Life of this patent
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Abstract
Salts of iodomethanesulfonic acid and an organic base, more particularly, glucamine, N-alkyl- and N, N-dialkylglucamines and N-hydroxyalkyl- and N,N-di-hydroxyalkylglucamines, are useful as X-ray contrast agents, especially for spinal X-ray examination.
Claims11
A myelographic salt of iodomethanesulfonic acid with an amine selected from the group consisting of glucamine, N-alkylglucamine, N,N-dialkylglucamine and hydroxyalkylglucamines of the latter and former alkylglucamines containing more than one carbon atom in the alkyl radical, said amine in all cases having up to a total of four carbon atoms in the alkyl portion.
A salt of claim l, wherein the amine is selected from the group consisting of N-methylglucamine;
- N,N-dimethylglucamine;
- N-ethylglucamine;
- N-methyl,N-ethylglucamine;
- N,N-diethylglucamine;
- N-.beta.-hydroxyethylglucamine;
- N-methyl,N-.beta.-hydroxyethylglucamine and N,N-di-.beta.-hydroxyethylglucamine.
Dependencies are inferred from the claim text.