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US 3,932,407 AGranted
Optionally substituted 1,2,3,5-tetrahydroimidezo(2,1-b)-quinazolin-2-ones and 6(H)-1,2,3,4-tetrahydropyimido(2,1-b)quinazolin-2-ones
AssigneeBristol-Myers Company
InventorsWarren Neil Beverung, Jr., Anthony Partyka
Life of this patent
Estimating the term…
Abstract
Optionally substituted 1,2,3,5-tetrahydroimidazo[2,1-b]-quinazolin-2-ones and 6-[H]-1,2,3,4-tetrahydropyrimido[2,1-b]-quinazolin-2-ones or the pharmaceutically acceptable salts thereof are compounds useful as blood platelet anti-aggregative and/or antihypertensive and/or bronchodilator agents in mammals, including humans.
Claims19
The compound having the formula ##SPC29##
- in which R.sup.1 is H, phenyl or (lower)alkyl, R.sup.2 and R.sup.3 when different are hydrogen, chloro, bromo, fluoro, CF.sub.3, SO.sub.3 H, hydroxy, (lower)alkyl or (lower) alkoxy, nitro, amino or phenyl, R.sup.2 and R.sup.3 when alike are hydrogen, bromo, chloro, fluoro, hydroxy, (lower)alkyl of 1 to 3 carbon atoms or (lower)alkoxy of 1 to 3 carbon atoms, or when taken together R.sup.2 and R.sup.3 are methylenedioxy or the moiety -CH=CH-CH=CH-, and n is an integer of 1 or 2;
- or a pharmaceutically acceptable acid addition salt thereof.
The compound having the formula ##SPC35##
- or an acid addition salt thereof.
The compound having the formula ##SPC36##
- or an acid addition salt thereof.
Dependencies are inferred from the claim text.