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US 2026/0308703 A1Published application
Crispr-cas-based novel guide rna capable of specific detection of norovirus gii.4 and application thereof
AssigneePulmuone Co., Ltd.
InventorsSang Yong LEE, Young Min PARK, Sang Gu KIM, Sang Yoon LEE, Hyo Yul LEE
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Abstract
The present invention relates to a CRISPR-Cas-based novel guide RNA capable of specific detection of norovirus GII.4 and a method for, by using same, the detection of norovirus GII.4 and the diagnosis of infection thereby. Using the guide RNA provided by the present invention, norovirus GII.4 in specimens can be rapidly detected with very high sensitivity and specificity.
Claims13
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A composition for detecting norovirus GII.4 comprising:
- a guide RNA specific for norovirus GII.4 comprising the nucleotide sequence of SEQ ID NO:
- 1;
- a forward primer comprising the nucleotide sequence of SEQ ID NO:
- 5;
- a reverse primer comprising the nucleotide sequence of SEQ ID NO. 7;
- and
- a CRISPR-associated protein.
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Dependencies are inferred from the claim text.