Loading patent…
OwnerLalita SAMANT, Amr Rafat ELHAMAMSY +1inventors
InventorsLalita SAMANT, Amr Rafat ELHAMAMSY, Rajeev Sharad SAMANT
Estimating the term…
Ribosome biogenesis is integral to cell proliferation, and its dysregulation is increasingly recognized as a hallmark of aggressive cancers. To understand these better, various embodiments of the present disclosure develop a score (the RB score) that captures overall ribosome biogenesis activity in tumors. In various examples, higher RB scores can be linked to worse prognostic outcomes. By measuring various genes in ribosome biogenesis, various embodiments of the present disclosure can more accurately predict which tumors are likely to progress faster or respond to immunotherapy. Described herein are kits, methods, and systems relating to determination of a ribosomal biogenesis score. Such a score can be utilized, for example, to determine or otherwise aid in the determination of a disease diagnosis or therapeutic regime, for example, in cancers.
A method of identifying a tumor status, the method comprising:
A non-transitory, computer-readable medium comprising machine-readable instructions that, when executed by a processor of a computing device, cause the computing device to at least:
A system for determining a tumor status in one or more samples from a subject, comprising:
Dependencies are inferred from the claim text.