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US 2026/0308679 A1Published application
Plasmonic nanoantenna and use of same in single molecule sequencing
AssigneeSwan Genomics Pty Ltd
InventorsLawrence LEE, Min HUANG, James BROWN, Alexander Daniel MARS
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Abstract
The present disclosure relates generally to methods of sequencing nucleic acid molecules, such as DNA and more specifically single molecules of DNA, using polymerase enzyme located within an area of electrical field enhancement. The present disclosure also relates to plasmonic nanoantenna which may be used in nucleic acid sequencing, methods of making said nanoantenna, arrays comprising said nanoantenna and methods of using said nanoantenna and arrays in single molecule sequencing technologies.
Claims21
-106. (canceled)
A system comprising:
- a) two plasmonic particles;
- b) a nucleic acid scaffold coupled to the two plasmonic particles;
- and
- c) a protein, wherein the protein is bound to the nucleic acid scaffold.
1 more element
A method comprising:
- a) providing:
- i) two plasmonic particles;
- ii) a nucleic acid scaffold coupled to the two plasmonic particles;
- and
- iii) a protein, wherein the protein is bound to the nucleic acid scaffold;
- and
- b) with aid of the two plasmonic particles, generating an electrical field at the protein bound to the nucleic acid scaffold.
4 more elements
Dependencies are inferred from the claim text.