Cis-8-(3,5-Difluorophenyl)-8-(dimethylamino)-1,3-diazaspiro[4.5]decan-2-one derivatives

A compound according to general formula (I)

• wherein
• A1 represents N or CR1;
• A2 represents N or C;
• A3 represents N or CH;
• A4 represents N or CH;
• A5 represents N or C;
• with the proviso that one or two of A1, A2, A3, A4 and A5 mean N, whereas the remaining three or four of A1, A2, A3, A4, and A5 do not mean N;
• R1 represents —H, —CH3 or ═O;
• R2 represents
• —C1-C6-alkyl, linear or branched, saturated or unsaturated, unsubstituted or substituted with one, two, three or four substituents independently selected from —F and —OH;
• —C3-C7-heterocycloalkyl, saturated or unsaturated, unsubstituted or substituted with one, two, three or four substituents independently selected from —F, —OH and —CH3;
• —S(O)2—C1-C4-alkyl, linear, branched or cyclic, unsubstituted or substituted with one, two or three substituents —F;
• —O—C1-C6-alkyl, linear or branched, saturated or unsaturated, unsubstituted or substituted with one, two, three or four substituents independently selected from —F, —OH and —OCH3;
• —O—C3-C8-cycloalkyl, saturated or unsaturated, unsubstituted or substituted with one, two, three or four substituents independently selected from —F, —OH and —CH3;
• or
• —O—C3-C7-heterocycloalkyl, saturated or unsaturated, unsubstituted or substituted with one, two, three or four substituents independently selected from —F and —OH;
• or R1 and R2 together with A1 and A2 form a ring and mean —CH═CN—NH—;
• R3 represents —H or —CH3;
• R4 and R5 both represent either each —H or together mean ═O;
• or a physiologically acceptable salt thereof.