Crystalline forms of 3-(5,7-difluoro-4-oxo-1,4-dihydroquinolin-2-yl)-4-(methylsulfonyl)benzonitrile
OwnerMark E. Scott, Michael J. Geier +5inventors
InventorsMark E. Scott, Michael J. Geier, Yaohui Huang, Runyan Li, Xiaoyang Wang, Hong Deng, Tingting Fan
Life of this patent
Estimating the term…
Abstract
Provided are crystalline forms of 3-(5,7-difluoro-4-oxo-1,4-dihydroquinolin-2-yl)-4-(methylsulfonyl)benzonitrile, pharmaceutical compositions comprising the crystalline form, and their use in treating conditions associated with the suppression of PPARG cell signaling.
Claims27
Crystalline Form B, C, D, E, F, G, G′, or H of a compound having the structural formula:
3-10. (canceled)
12-18. (canceled)
20-26. (canceled)
28-33. (canceled)
35-41. (canceled)
43-49. (canceled)
51-57. (canceled)
59-65. (canceled)
A crystalline form of a hydrochloric acid salt of a compound having the structural formula:
68-73. (canceled)
A crystalline form of a methanesulfonic acid salt of a compound having the structural formula:
76-80. (canceled)
Dependencies are inferred from the claim text.