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US 2026/0306719 A1Published application
Trodusquemine-coated balloon for targeted treatment of atherosclerosis
AssigneeBard Peripheral Vascular, Inc.
InventorMelissa Boyle
Life of this patent
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Abstract
The present disclosure concerns coatings for angioplastic balloons that deliver trodusquemine to the vessel walls during the expansion of the balloon in situ. The hydrophobic nature of the drug combined with the mechanism of action allow for site specific treatment to wear away plaque within the vessel walls. The site specific delivery offers the potential for lower dosing and the choice of trodusquemine provides a further alternative to conventional medications.
Claims17
A balloon catheter for delivering a therapeutic agent to a blood vessel, the balloon catheter comprising:
- an elongate member having a lumen and a distal end;
- an expandable balloon attached to the distal end of the elongate member and in fluid communication with the lumen;
- and
- a coating layer overlying an exterior surface of the expandable balloon, the coating layer comprising trodusquemine or a polymer microparticle containing trodusquemine and an excipient.
1 more element
Dependencies are inferred from the claim text.