Pharmaceutical compositions of gd-based contrast agents
AssigneeBracco Imaging S.P.A.
InventorsZsolt BARANYAI, Mariangela BOCCALON, Federica BUONSANTI, Federico CRIVELLIN, Alessandro MAIOCCHI, Roberta MAZZON, Fabio TEDOLDI, Fulvio UGGERI
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Abstract
The present invention relates to pharmaceutical compositions comprising an gadolinium-complex and a saturated macrocyclic tetraamine that find application in diagnostic imaging as diagnostic agents, in particular as contrast agents having improved tolerability, specifically in Magnetic Resonance Imaging (MRI), and to their preparation.
Claims4
1-12. (canceled)
Salt of the ((4RS)-[4-carboxy-5,8,11-tris(carboxymethyl)-1-phenyl-2-oxa-5,8,11-triazatridecan-13-oato (5-)] gadolinate (2-) dihydrogen compound with 1,4,7,10-tetrazacyclododecane (1:1) of formula
Dependencies are inferred from the claim text.